Inflammatory cloacogenic polyp is a rare condition arising from the transit
ional zone of the anorectal junction. It is benign but may macroscopically
resemble anorectal malignancy. Inflammatory cloacogenic polyp was diagnosed
in two patients with rectal bleeding and polypoid growths at the anorectal
junction. The lesions were best visualized with an endoscope retroflexed i
n the rectum. Accurate diagnosis was dependent on histological examination.
The histological similarities to solitary rectal ulcer syndrome and other
mucosal prolapse conditions are discussed, and the literature on inflammato
ry cloacogenic polyp and its management reviewed. Eur J Gastroenterol Hepat
ol 12:247-250 (C) 2000 Lippincott Williams & Wilkins.