Two boys aged 6 and 9 years presented with persistent sharply circumscribed
perianal erythema. One boy had no other skin findings; the other had addit
ional lesions on the genitalia and extremities. The diagnosis of perianal s
treptococcal dermatitis was made after streptococci were cultured from skin
swabs. This primarily childhood disease should be distinguished from candi
diasis and perianal atopic dermatitis. As in our cases, topical therapy is
usually ineffective and oral penicillin remains the treatment of choice.