Adolescent substance abuse, with its heterogeneity, its complexity and its
association with behavioural. physical and mental health problems is of inc
reasing interest to many; the politician, the economist, clinicians and res
earchers, families and young people themselves. Data concerning the prevale
nce and trends in use of a range of substances in different countries, cult
ures and different groups are reviewed. The influence of associated mental
and physical health problems, the multiple definitions applied to use and a
buse and the confounding effect of different ideologies and cultural differ
ences are considered. There is now much interest in the understanding of ri
sk and protective influences, including multi focused prevention programmes
among vulnerable young people. Some positive effects of universal preventi
on programmes are reported, although too often they lack thoroughness in pr
ogramme implementation, data collection and follow up. Indeed compared to t
he adult addiction literature there is a death of research on adolescent tr
eatment outcomes. Research needs to address treatment and cost effectivenes
s in different settings with different groups. The evidence tends to suppor
t multi faceted interventions for high risk youths. However, the use of evi
dence based programmes with a scientific basis should be supported and impl
emented.