Common plastic drug packaging material available in Australia and in Asia w
as analyzed using a standard protocol including optical examination, UV-vis
ible and Fourier transform infrared spectrometry. The aims were to determin
e whether there are significant differences between different sources, to e
stablish the evidential value of these examinations, and to build a databas
e of common packaging material.
Visual examination was the most effective means for discriminating samples.
Thickness and weight measurements provided useful information. Visualizati
on of machining marks using crossed polarized light was found to be useful
in the comparison process. UV-visible spectrophotometry has some value for
distinguishing samples. Fourier transform infrared analysis was a good tech
nique for determination of the polymer composition of the packaging. Signif
icant differences were observed between Australian and overseas samples.
The "Australian Database of Drug Packaging Materials" was created to system
atically collate all of the collected data for application on personal comp
uters. It is concluded that the properties of plastic packaging materials c
an be excellent indicators for identifying the specific brand or origin of
the packaging.