Population data on the thirteen CODIS core short tandem repeat loci in African Americans, US Caucasians, Hispanics, Bahamians, Jamaicans, and Trinidadians

Citation
B. Budowle et al., Population data on the thirteen CODIS core short tandem repeat loci in African Americans, US Caucasians, Hispanics, Bahamians, Jamaicans, and Trinidadians, J FOREN SCI, 44(6), 1999, pp. 1277-1286
Citations number
27
Categorie Soggetti
Research/Laboratory Medicine & Medical Tecnology
Journal title
JOURNAL OF FORENSIC SCIENCES
ISSN journal
00221198 → ACNP
Volume
44
Issue
6
Year of publication
1999
Pages
1277 - 1286
Database
ISI
SICI code
0022-1198(199911)44:6<1277:PDOTTC>2.0.ZU;2-T
Abstract
Allele distributions for 13 tetrameric short tandem repeat (STR) loci, CSF1 PO, FGA, TH01, TPOX, VWA, D3S1358, D5S818, D7S820, D8S1179, D13S317, D16S53 9, D18S51, and D21S11, were determined in African American, United States C aucasian, Hispanic, Bahamian, Jamaican, and Trinidadian sample populations. There was little evidence for departures from Hardy-Weinberg expectations (HWE) in any of the populations. Based on the exact test, the loci that dep arted significantly from HWE are: D21S11 (p = 0.010, Bahamians); CSF1PO (p = 0.014, Trinidadians); TPOX (p = 0.011, Jamaicans and p = 0.035, U.S. Cauc asians); and D16S539 (p = 0.043, Bahamians). After employing the Bonferroni correction for the number of loci analyzed (i.e., 13 loci per database), t hese observations are not likely to be significant. There is little evidenc e for association of alleles between the loci in these databases. The allel ic frequency data are similar to other comparable data within the same majo r population group.