Population data on the thirteen CODIS core short tandem repeat loci in African Americans, US Caucasians, Hispanics, Bahamians, Jamaicans, and Trinidadians
B. Budowle et al., Population data on the thirteen CODIS core short tandem repeat loci in African Americans, US Caucasians, Hispanics, Bahamians, Jamaicans, and Trinidadians, J FOREN SCI, 44(6), 1999, pp. 1277-1286
Allele distributions for 13 tetrameric short tandem repeat (STR) loci, CSF1
PO, FGA, TH01, TPOX, VWA, D3S1358, D5S818, D7S820, D8S1179, D13S317, D16S53
9, D18S51, and D21S11, were determined in African American, United States C
aucasian, Hispanic, Bahamian, Jamaican, and Trinidadian sample populations.
There was little evidence for departures from Hardy-Weinberg expectations
(HWE) in any of the populations. Based on the exact test, the loci that dep
arted significantly from HWE are: D21S11 (p = 0.010, Bahamians); CSF1PO (p
= 0.014, Trinidadians); TPOX (p = 0.011, Jamaicans and p = 0.035, U.S. Cauc
asians); and D16S539 (p = 0.043, Bahamians). After employing the Bonferroni
correction for the number of loci analyzed (i.e., 13 loci per database), t
hese observations are not likely to be significant. There is little evidenc
e for association of alleles between the loci in these databases. The allel
ic frequency data are similar to other comparable data within the same majo
r population group.