The effect of water on the rhodium-catalyzed carbonylation of isopropylallylamine

The effects of the presence of water on the rhodium-catalyzed carbonylation of isopropylallylamine were studied as a function of the following paramet ers: reaction temperature; water content; presence of phosphines; solvent p olarity and presence of bulky ions. It turned out that the reaction is stro ngly dependent on the temperature and that water seems to behave both as a source of hydrogen and as a ligand in the active species. The phosphine lig ands showed no effect since in the presence of water they were all converte d to their corresponding oxides. (C) 2000 Elsevier Science B.V. All rights reserved.