Volume expansion in relation to the gas-antisolvent process

The underlying work is part of an extensive study to develop appropriate th ermodynamic criteria for an optimum gas-antisolvent (GAS) process. It turne d out that the 'classical' definition of volume expansion is inappropriate to define these criteria. An alternative definition of this property has be en introduced in this work. This study was carried out for a number of bina ry and ternary systems of which the experimental data were taken from liter ature. The Peng-Robinson equation of state was used to describe the fluid p hases, whereas for the solid phase an independent relationship was applied. It will be shown that the definition for liquid-phase volume expansion as proposed in this work is useful for the selection of the optimum pressure f or the GAS process. (C) 2000 Elsevier Science B.V. All rights reserved.