Activity revealed in MRI of multiple sclerosis without contrast agent - A preliminary report

Disease activity in multiple sclerosis is usually accompanied by blood-brai n barrier disruption, which can be assessed with contrast-enhanced magnetic resonance imaging (MRI). This paper describes a technique that gives infor mation about disease activity using magnetization transfer MRT. Image combi nation methods using follow-up scans, like the one presented here, have the potential to show MS lesions that correlate with enhancement. (C) 2000 Els evier Science Inc. All rights reserved.