Distribution of 4.5S1. RNA among rodents and conservation of its nucleotide sequence

Citation
Ik. Gogolevskaya et Da. Kramerov, Distribution of 4.5S1. RNA among rodents and conservation of its nucleotide sequence, MOL BIOL, 34(1), 2000, pp. 6-11
Citations number
26
Categorie Soggetti
Molecular Biology & Genetics
Journal title
MOLECULAR BIOLOGY
ISSN journal
00268933 → ACNP
Volume
34
Issue
1
Year of publication
2000
Pages
6 - 11
Database
ISI
SICI code
0026-8933(200001/02)34:1<6:DO4RAR>2.0.ZU;2-B
Abstract
It has been shown that small nuclear 4.5S1 RNA and its homologous DNA seque nces occur only in three rodent families: Muridae, Cricetidae, and Spalacid ae. This RNA is suggested to arise about the same evolutionary time as shor t retroposon B2 relative to it. The nucleotide sequences of golden hamster and common mole rat 4.5S1 RNA are highly conservative, as compared with the rat one, which can point out its functional role despite the narrow specie s range of its distribution.