The purpose of this study was to examine the influence of vigorous acute ex
ercise on nocturnal sleep that had been disrupted by high doses (1200 mg) o
f caffeine throughout the daytime. Eight moderately fit, young males with a
history of moderate caffeine use completed four conditions in a within-sub
jects, counterbalanced design: 60 min of (i) cycling at 60% VO2peak or (ii)
quiet rest following placebo consumption, (iii) cycling, or (iv) quiet res
t following the consumption of a high dose of caffeine. Each condition was
performed twice from 1615-1715 h and followed by all-night polysomnographic
recording. Subjects consumed two blinded 200-mg capsules of either lactose
placebo or caffeine upon awakening, at 1600 h, and 2 h before bedtime. Sta
te anxiety was assessed at bedtime. Criterion scores consisted of the mean
data across the two days in each condition. Sleep data were analyzed using
a condition (exercise versus quiet rest) by drug (caffeine versus placebo)
repeated-measures ANOVA. Caffeine elicited sleep disturbance that was less
than previously reported. Exercise attenuated selected sleep disturbances t
o a small degree. In general, the effects of exercise on sleep were not gre
ater following caffeine compared to placebo. Indeed, increases in slow-wave
sleep after exercise were approximately 1/3 smaller following caffeine tre
atment compared to placebo. (C) 2000 Elsevier Science Inc. All rights reser
ved.