Employment of a cellulosic polymer as carrier of diethylamine salicylate in topical formulations

Authors
Gallardo, V Zouaki, Y Parera, A Ruiz, MA
Citation
V. Gallardo et al., Employment of a cellulosic polymer as carrier of diethylamine salicylate in topical formulations, REACT FUNCT, 43(3), 2000, pp. 351-357
Citations number
11
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
REACTIVE & FUNCTIONAL POLYMERS
ISSN journal
13815148 → ACNP
Volume
43
Issue
3
Year of publication
2000
Pages
351 - 357
Database
ISI
SICI code
1381-5148(20000315)43:3<351:EOACPA>2.0.ZU;2-G
Abstract
Adsorption-desorption of diethylamine salicylate on latex particles have be en studied. Time, pH, concentration and electrokinetic characteristics of t he active principle at which maximum absorption occurred were determined. D esorption of the drug from latex polymer particles was studied in three dif ferent vehicles. The findings suggest that solubility of diethylamine salic ylate is the main factor affecting release of the drug from the excipients tested. (C) 2000 Elsevier Science B.V. All rights reserved.