Mild method for the synthesis of amidines by the electrophilic activation of amides

Authors
Charette, AB Grenon, M
Citation
Ab. Charette et M. Grenon, Mild method for the synthesis of amidines by the electrophilic activation of amides, TETRAHEDR L, 41(11), 2000, pp. 1677-1680
Citations number
14
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
11
Year of publication
2000
Pages
1677 - 1680
Database
ISI
SICI code
0040-4039(20000311)41:11<1677:MMFTSO>2.0.ZU;2-3
Abstract
The synthesis of amidines was achieved by the addition of amines to amides that were previously activated with trifluoromethanesulfonic anhydride (tri flic anhydride) and pyridine. Various disubstituted and trisubstituted amid ines were prepared in yields up to 84%. (C) 2000 Elsevier Science Ltd. All rights reserved.