Synthesis of 1-benzoyl-3-alkylthioureas by transamidation under microwave in dry media

Authors
Marquez, H Perez, ER Plutin, AM Morales, M Loupy, A
Citation
H. Marquez et al., Synthesis of 1-benzoyl-3-alkylthioureas by transamidation under microwave in dry media, TETRAHEDR L, 41(11), 2000, pp. 1753-1756
Citations number
13
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
11
Year of publication
2000
Pages
1753 - 1756
Database
ISI
SICI code
0040-4039(20000311)41:11<1753:SO1BTU>2.0.ZU;2-C
Abstract
1-Benzoyl-3,3-diethylthiourea was transamidated with several amines to the corresponding 1-benzoyl-3-alkylthioureas in open vessels under microwave ir radiation using a domestic oven. The syntheses were performed in solvent-fr ee conditions on potassium fluoride impregnated alumina. Yields were dramat ically improved in comparison with classical heating under the same conditi ons. (C) 2000 Published by Elsevier Science Ltd. All rights reserved.