Efficient and regioselective 4-amino-de-chlorination of 2,4,6-trichloropyrimidine with N-sodium carbamates

Authors
Zanda, M Talaga, P Wagner, A Mioskowski, C
Citation
M. Zanda et al., Efficient and regioselective 4-amino-de-chlorination of 2,4,6-trichloropyrimidine with N-sodium carbamates, TETRAHEDR L, 41(11), 2000, pp. 1757-1761
Citations number
20
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
11
Year of publication
2000
Pages
1757 - 1761
Database
ISI
SICI code
0040-4039(20000311)41:11<1757:EAR4O2>2.0.ZU;2-0
Abstract
4-N-Alkoxycarbonyl-2,6-dichloropyrimidines have been synthesized with good to excellent regioselectivity and yields from 2,4,6-trichloropyrimidine and N-sodium carbamates in DMF, at room temperature, in 15-30 minutes. (C) 200 0 Elsevier Science Ltd. All rights reserved.