The use of atypical neuroleptic drugs in child and adolescent psychiatry

Citation
H. Remschmidt et al., The use of atypical neuroleptic drugs in child and adolescent psychiatry, Z KIND JUG, 28(1), 2000, pp. 45-57
Citations number
56
Categorie Soggetti
Psychiatry
Journal title
ZEITSCHRIFT FUR KINDER-UND JUGENDPSYCHIATRIE UND PSYCHOTHERAPIE
ISSN journal
14224917 → ACNP
Volume
28
Issue
1
Year of publication
2000
Pages
45 - 57
Database
ISI
SICI code
1422-4917(200002)28:1<45:TUOAND>2.0.ZU;2-2
Abstract
Atypical neuroleptic drugs have enriched our treatment programs, especially in childhood and adolescent schizophrenia. Reviewed here is the use of aty pical neuroleptics in children and adolescents with a schizophrenic disorde r. The receptor binding profile and pharmacological properties, indications , side effects, clinical application, and trials of atypical neuroleptic dr ugs are compared to the classical neuroleptic drug haloperidol in the treat ment of adolescent schizophrenia. Special attention is paid to the most com mon atypical neuroleptics clozapine, olanzapine and risperidone since most studies are carried out with these compounds, most often with clozapine, Mo re clinically controlled trials have to be conducted since only one has bee n performed to date. The place of atypical neuroleptic drugs is discussed a nd further studies are necessary in order to differentiate, and eventually broaden the spectrum of the indications tested thus far.