Treatment with immune suppression and bone marrow transplantation has impro
ved the response rates and survival of patients with aplastic anemia. Measu
rement of response requires that common endpoints be recorded at specific t
imes. There has been no agreement on such parameters for patients with apla
stic anemia. In this paper issues related to measurement of response are re
viewed and criteria for response are proposed. Adoption of uniform criteria
would facilitate comparisons of treatment efficacy. Copyright (C) 2000 S.
Karger AG, Basel.