Seven cases of hydrogen cyanide gas poisoning which occurred in an industri
al building in Hong Kong are presented here. Two of them were more severely
injured and required specific antidotal treatment. The other five were mil
d and responded to supportive treatment alone. All except one patient recov
ered completely. Cyanide poisoning is relatively uncommon in urbanized area
, so high index of suspicion is important for early diagnosis and treatment
. We believe that prevention of cyanide poisoning can be achieved by proper
storage of chemicals, and by enforcing rescuers to wear special chemical p
rotective clothing to avoid systemic poisoning because of dermal absorption
of hydrogen cyanide gas. As there are newer and safer cyanide antidotes av
ailable, each emergency department should have a stock of updated products
such as hydroxocobalamin. (Am J Emerg Med 2000;18:172-175, Copyright (C) 20
00 by W.B. Saunders Company).