Potential allogeneic graft-versus-tumor effect in a patient with ovarian cancer

Authors
Bay, JO Choufi, B Pomel, C Dauplat, J Durando, X Tournilhac, O Travade, P Plagne, R Blaise, D
Citation
Jo. Bay et al., Potential allogeneic graft-versus-tumor effect in a patient with ovarian cancer, BONE MAR TR, 25(6), 2000, pp. 681-682
Citations number
6
Categorie Soggetti
Hematology,"Medical Research Diagnosis & Treatment
Journal title
BONE MARROW TRANSPLANTATION
ISSN journal
02683369 → ACNP
Volume
25
Issue
6
Year of publication
2000
Pages
681 - 682
Database
ISI
SICI code
0268-3369(200003)25:6<681:PAGEIA>2.0.ZU;2-T
Abstract
A 33-year-old woman developed progressive ovarian cancer resistant to class ical chemotherapy agents. We performed a bone marrow allograft after a myel oablative regimen. During hematological recovery, she developed acute graft -versus-host disease (GVHD). From this time her tumor diminished progressiv ely. One year post transplant she has limited chronic liver GVHD and is sti ll free of disease. The complete remission of advanced ovarian cancer was p robably related to the GVHD which might therefore provide a new treatment o ption for this disease.