Monitoring the secretion from single cells with temporal and spatial resolution

The secretion from cells plays a significant role in life activities and in the fields of neurobiology, cell biology, clinic, pathology, pharmacology etc. Thus to investigate the secretion at the single cell level with the de veloping methods is a frontier cross-discipline research activity. The cont ents, methods and new progress of this research have been reviewed by elect rochemical monitoring combined with patch-clamp techniques, fluorescent det ection and immunoassay, and the prospects on the frontier of the research a rea have been discussed.