Biochip as a new research field has enjoyed its rapid development in the pa
st 10 years. Using microfabrication technology, thousands or hundred thousa
nds of biological molecules can be assembled on a centimeter square microch
ip. Those chip-based devices can be used to analyze mutations, antigens, ce
lls, etc. Compared with the traditional analytical instruments, chip-based
micro total analytical systems have many advantages, such as reduced size,
lower consumption of both reagents and energy, contamination-free, etc. Bio
chip technology is believed to revolutionize the future research in life sc
iences, disease diagnosis, drug discovery, forensic sciences and outer spac
e exploitation in the coming century.