We show that up to a translation each automorphism of the derived category
(DX)-X-b of coherent sheaves on a weighted projective line X, equivalently
of the derived category D(b)A of finite dimensional modules over a derived
canonical algebra A, is composed of tubular mutations and automorphisms of
X. In the case of genus one this implies that the automorphism group is a s
emi-direct product of the braid group on three strands by a finite group.
Moreover we prove that most automorphisms lift from the Grothendieck group
to the derived category.