Starting from the experimental evidence that high-energy nucleus-nucleus co
llisions cannot be described in terms of superpositions of elementary nucle
on-nucleon interactions, we analyze the possibility that memory effects and
long-range forces imply a non-extensive statistical regime during high-ene
rgy heavy-ion collisions. The relevance of these statistical effects and th
eir compatibility with the available experimental data are discussed. In pa
rticular, we show that theoretical estimates obtained in the framework of t
he generalized non-extensive thermostatistics, can reproduce the shape of t
he pion transverse mass spectrum and explain the different physical origin
of the transverse momentum correlation function of the pions emitted during
the central Pb + Pb and during the p + p collisions at 158 GeV.