Initial experience with a modification of the follicle aspiration, sperm injection, and assisted rupture technique

Objective: To establish cycle fecundity with a modification of the follicle aspiration, sperm injection, and assisted rupture (FASIAR) technique. Design: Prospective, observational study. Setting: University and health maintenance organization-based infertility c enters. Patient(s): Infertile couples were enrolled from our professional practices . All patients were less than or equal to 41 years of age and had documenta tion of at least one patent tube. Intervention(s): After administration of clomiphene citrate, patients were given an intramuscular injection of hCG when the lead ovarian follicle was >16-18 mm in diameter by transvaginal ultrasonography. A modified FASIAR pr ocedure was performed 22 to 28 hours after hCG injection. Main Outcome Measure(s): Clinical pregnancy rate. Result(s): No clinical pregnancies were observed with the modified FASIAR t echnique. Conclusion(s): The FASIAR technique is still an attractive and economical t echnique. Our modification of the FASIAR technique, however, resulted in a suboptimal cycle fecundity. (C) 2000 by American Society for Reproductive M edicine.