In vivo-induced genes in Pseudomonas aeruginosa

Authors
Handfield, M Lehoux, DE Sanschagrin, F Mahan, MJ Woods, DE Levesque, RC
Citation
M. Handfield et al., In vivo-induced genes in Pseudomonas aeruginosa, INFEC IMMUN, 68(4), 2000, pp. 2359-2362
Citations number
14
Categorie Soggetti
Immunology
Journal title
INFECTION AND IMMUNITY
ISSN journal
00199567 → ACNP
Volume
68
Issue
4
Year of publication
2000
Pages
2359 - 2362
Database
ISI
SICI code
0019-9567(200004)68:4<2359:IVGIPA>2.0.ZU;2-C
Abstract
In vivo expression technology was used for testing Pseudomonas aeruginosa i n the rat lung model of chronic infection and in a mouse model of systemic infection. Three of the eight ivi proteins found showed sequence identity t o known virulence factors involved in iron acquisition via an open reading frame (called pvdI) implicated in pyoverdine biosynthesis, membrane biogene sis (FtsY), and adhesion (Hag2).