Disparate requirement for T cells in resistance to mucosal and acute systemic candidiasis

Authors
Jones-Carson, J Vazquez-Torres, A Warner, T Balish, E
Citation
J. Jones-carson et al., Disparate requirement for T cells in resistance to mucosal and acute systemic candidiasis, INFEC IMMUN, 68(4), 2000, pp. 2363-2365
Citations number
19
Categorie Soggetti
Immunology
Journal title
INFECTION AND IMMUNITY
ISSN journal
00199567 → ACNP
Volume
68
Issue
4
Year of publication
2000
Pages
2363 - 2365
Database
ISI
SICI code
0019-9567(200004)68:4<2363:DRFTCI>2.0.ZU;2-Q
Abstract
Although highly susceptible to orogastric candidiasis, T-cell receptor delt a- and alpha-chain knockout mice, deficient in gamma delta and alpha beta T cells, respectively, were found to be resistant to disseminated candidiasi s of endogenous origin and to acute systemic candidiasis (resulting from in travenous injection).