Resistant bacteria are emerging in Latin America as a real threat to the fa
vorable outcome of infections in community- and hospital-acquired infection
s. Despite present extensive surveillance, healthcare workers who most need
the information may be unaware of this growing problem. Outbreaks of menin
gococci with diminished susceptibility to penicillin have been reported in
the region; a constant increase of resistance to penicillin in pneumococci
and poor activity of commonly used oral antibiotics for the treatment of co
mmunity-acquired urinary tract infections have made the treatment of these
infections more difficult. Reports from tertiary hospitals are similar to m
any other areas of the world, with increasing frequency of Klebsiella pneum
oniae-carrying extended-spectrum beta-lactamase, multiresistant strains of
Pseudomonas aeruginosa and Acinetobacter baumanni in ICU settings, and repo
rts of methicillin-resistant Staphylococcus aureus and vancomycin-resistant
enterococci. A surveillance network readily accessible to those who prescr
ibe antibiotics in Latin America is highly desirable.