Countries in the Americas have led the world in conquering infectious disea
ses preventable through vaccination. In 1971, the Western hemisphere achiev
ed smallpox eradication. In 1991, the Americas were free of indigenous tran
smission of wild poliovirus. in 1998, overall regional vaccination coverage
was 86% for diphtheria-pertussis-tetanus, 89% for oral poliovirus vaccine
3, 98% for bacille Calmette-Guerin vaccine, and 85% for measles. These figu
res confirm that most of the children in the Americas are protected against
these diseases. The breakthroughs obtained in immunization have stimulated
countries to promote new initiatives aimed at the control and eradication
of other vaccine-preventable diseases and to introduce new vaccines into ro
utine schedules. In the 21st century, vaccines will remain the most cost-ef
fective means of preventing diseases and avoiding expensive treatment costs
.