We studied 645 full-term low-risk women in early labour in 6 units to evalu
ate the effects of maternal characteristics and obstetric management in ear
ly labour on the use of epidural analgesia, and to analyse the relationship
between epidural analgesia, progress of labour and mode of delivery using
multiple logistic regression. Among variables present in early labour, null
iparity, ethnicity and obstetric unit were the strongest predictors of epid
ural analgesia requirement. In nulliparous women, obstetric unit affected u
se of epidural analgesia (P<0.05) and induction of labour was associated wi
th increased use of epidural analgesia (odds ratio 3.45, 95% CI: 1.45-7.90)
. In multiparous women, only ethnicity was statistically significant (P<0.0
5). Epidural analgesia was associated with longer labours and more instrume
ntal deliveries (odds ratio 2.93, 95%-CI: 1.48-5.83). In the epidural group
, however, we found a positive correlation between first stage duration and
elapsed time before epidural analgesia. Furthermore rate of cervical dilat
ion was similar in the non epidural group throughout the first stage (mean
3.41 cm/h, 95% CI: 3.19 3.63) and in the epidural group after epidural anal
gesia decision (mean 3.99, 95% CI: 2.96 5.02), while the mean cervical dila
tation rate before epidural analgesia was 0.88 cm/h (95% CI: 0.72-1.04), Th
e need for epidural analgesia is, therefore, multifactorial and difficult t
o predict. Whereas nulliparity increases epidural analgesia requirement, da
ta on the progress of labour before pain relief suggest that epidural analg
esia is a marker of pain severity and/or labour failure rather than the cau
se of delayed progress in low-risk pregnancies.