A novel non-toxic fixative solution of Complucad for histology and immunohistochemistry

Although there are many fixatives available, there is no one that can be us ed universally for histological, histopathological, and immunohistochemical techniques. In addition. the majority of fixatives are toxic. We have used a fixative called Complucad that preserves morphology and allows subsequen t treatment, conservation, and staining of the different tissues fur a vari ety of techniques. Complucad works rapidly and is not toxic to eyes, skin, and respiratory tract. We describe the methodology and the results for its use on different rat tissues fixed with diverse solutions of Complucad for histology and immunohistology.