Kyanomycin, a complex of unusual anthracycline-phospholipid hybrids from Nonomuria species

Authors
Pfefferle, CM Breinholt, J Olsen, CE Kroppenstedt, RM Wellington, EMH Gurtler, H Fiedler, HP
Citation
Cm. Pfefferle et al., Kyanomycin, a complex of unusual anthracycline-phospholipid hybrids from Nonomuria species, J NAT PROD, 63(3), 2000, pp. 295-298
Citations number
8
Categorie Soggetti
Agricultural Chemistry","Pharmacology & Toxicology
Journal title
JOURNAL OF NATURAL PRODUCTS
ISSN journal
01633864 → ACNP
Volume
63
Issue
3
Year of publication
2000
Pages
295 - 298
Database
ISI
SICI code
0163-3864(200003)63:3<295:KACOUA>2.0.ZU;2-4
Abstract
A blue secondary metabolite complex, named kyanomycin (2), in addition to e psilon-rhodomycinone (1), was detected in the mycelium extract of Nonomuria sp. NN 22303 by HPLC-diode array and HPLC-electrospray mass spectrometry s creening. The chemical structures of the novel compounds were determined to be unusual anthracycline-phosphatidylethanolamine hybrids by spectroscopic and chemical degradation experiments.