7-epicylindrospermopsin, a toxic minor metabolite of the cyanobacterium Aphanizomenon ovalisporum from Lake Kinneret, Israel

Authors
Banker, R Teltsch, B Sukenik, A Carmeli, S
Citation
R. Banker et al., 7-epicylindrospermopsin, a toxic minor metabolite of the cyanobacterium Aphanizomenon ovalisporum from Lake Kinneret, Israel, J NAT PROD, 63(3), 2000, pp. 387-389
Citations number
12
Categorie Soggetti
Agricultural Chemistry","Pharmacology & Toxicology
Journal title
JOURNAL OF NATURAL PRODUCTS
ISSN journal
01633864 → ACNP
Volume
63
Issue
3
Year of publication
2000
Pages
387 - 389
Database
ISI
SICI code
0163-3864(200003)63:3<387:7ATMMO>2.0.ZU;2-9
Abstract
A toxic minor metabolite, 7-epicylindrospermopsin (1), was isolated from a culture of the cyanobacterium Aphanizomenon ovalisporum isolated from Lake Kinneret in Israel. Homonuclear and inverse-heteronuclear 2D NMR techniques , as well as HRMS and comparison of the NMR data with model compounds, enab led the structure determination of the new compound. Four polymethoxy-1-alk enes, 3-6, were isolated from the lipophilic extract of the cyanobacterium as well.