Nasimaluns A and B: neo-clerodane diterpenoids from Barringtonia racemosa

Authors
Hasan, CM Khan, S Jabbar, A Rashid, MA
Citation
Cm. Hasan et al., Nasimaluns A and B: neo-clerodane diterpenoids from Barringtonia racemosa, J NAT PROD, 63(3), 2000, pp. 410-411
Citations number
14
Categorie Soggetti
Agricultural Chemistry","Pharmacology & Toxicology
Journal title
JOURNAL OF NATURAL PRODUCTS
ISSN journal
01633864 → ACNP
Volume
63
Issue
3
Year of publication
2000
Pages
410 - 411
Database
ISI
SICI code
0163-3864(200003)63:3<410:NAABND>2.0.ZU;2-U
Abstract
An ethanolic extract of the roots of Barringtonia racemosa afforded two nov el neo-clerodane-type diterpenoids, methyl-15,16-epoxy-12-oxo-3,13(16),14-n eo-clerodatrien-18,19-olide-17-carboxylate (nasimalun A, 1) and dimethyl-15 ,16-epoxy-3,13(16),14-neo-clerodatrien-17,18-dicarboxylate (17-carboxymethy lhardwickiic acid methyl eater, nasimalun B, 2) by NMR and MS analyses and by comparison of their spectral data with related compounds. The relative s tereochemistry of the asymmetric centers in 1 and 2 was determined by selec tive 1D NOESY experiments.