BRYOSTATIN - A NOVEL ASYMMETRIC-SYNTHESIS OF THE C-27-C-34 FRAGMENT STARTING FROM (R)-CARVONE AS CHIRAL TEMPLATE

Authors
DEBRABANDER J KULKARNI BA GARCIALOPEZ R VANDEWALLE M
Citation
J. Debrabander et al., BRYOSTATIN - A NOVEL ASYMMETRIC-SYNTHESIS OF THE C-27-C-34 FRAGMENT STARTING FROM (R)-CARVONE AS CHIRAL TEMPLATE, Tetrahedron : asymmetry, 8(11), 1997, pp. 1721-1724
Citations number
22
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
8
Issue
11
Year of publication
1997
Pages
1721 - 1724
Database
ISI
SICI code
0957-4166(1997)8:11<1721:B-ANAO>2.0.ZU;2-I
Abstract
(R)-Carvone is a suitable chiral template for the synthesis of differe ntly protected (4S,6R,7R)-trihydroxy-1-octyne derivatives, the C-27-C- 34 fragment of bryostatins. Also other potentially interesting chiral building blocks are described. (C) 1997 Elsevier Science Ltd.