HIGHLY DIASTEREOSELECTIVE SYNTHESIS OF NEW OPTICALLY-ACTIVE AMINOALCOHOLS IN ONE-STEP FROM (-CAMPHOR AND (-)-FENCHONE())

Authors
GENOV M KOSTOVA K DIMITROV V
Citation
M. Genov et al., HIGHLY DIASTEREOSELECTIVE SYNTHESIS OF NEW OPTICALLY-ACTIVE AMINOALCOHOLS IN ONE-STEP FROM (-CAMPHOR AND (-)-FENCHONE()), Tetrahedron : asymmetry, 8(11), 1997, pp. 1869-1876
Citations number
23
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
8
Issue
11
Year of publication
1997
Pages
1869 - 1876
Database
ISI
SICI code
0957-4166(1997)8:11<1869:HDSONO>2.0.ZU;2-Q
Abstract
New optically active aminoalcohols have been prepared from CeCl3-activ ated (+)-camphor and (-)-fenchone and N-functionalized organolithium c ompounds. The aminoalcohols obtained catalyze the addition of diethylz inc to benzaldehyde in high yields and enantioselectivities up to 64%. (C) 1997 Elsevier Science Ltd.