Paradoxical vocal fold motion is a rare disorder in which adduction of the
folds occurs on inspiration. The disorder presents with signs of airway obs
truction and often airway distress, so proper diagnosis by the otorhinolary
ngologist is critical to subsequent management. We present a retrospective
review of 10 patients with the diagnosis of paradoxical vocal fold motion s
een over a 6-year period. Eight patients were females, and 6 required an ac
ute airway intervention at presentation; 3 patients eventually underwent tr
acheotomy for respiratory decompensation. Six patients had a prior diagnosi
s of asthma, and this was determined to contribute to their respiratory sta
tus. Five patients were treated with botulinum toxin and 2 with flexible na
solaryngoscopic biofeedback, which improved the outcome. A review of the li
terature confirms a female predominance of patients presenting with paradox
ical adduction and airway distress, often with a history of asthma and psyc
hopathology. Our experience with botulinum toxin and biofeedback suggests t
hat these procedures are viable treatment options in the management of pati
ents with this disorder.