B. Rigaud et al., BIOELECTRICAL-IMPEDANCE TECHNIQUES IN MEDICINE .1. BIOIMPEDANCE MEASUREMENT - 2ND SECTION - IMPEDANCE SPECTROMETRY, Critical reviews in biomedical engineering, 24(4-6), 1996, pp. 257-351
Electrical impedance spectrometry is an important application field of
bioimpedance measurements. After introducing the electrical propertie
s of biological tissues, this part presents instrumental aspects and a
pplications of electrical impedance spectrometry. The main instrumenta
l constraints encountered in spectrometric electrical impedance measur
ements are reviewed, focusing on low-frequency applications. Examples
of impedance cells and probes are presented and several instrumental s
etups operating in the frequency and time domain are described. Some e
xamples of applications are presented, including in vitro characteriza
tion and modeling of normal tissues, in vitro and in vivo characteriza
tion of cancerous tissues, and assessment of tissue perfusion/ischemia
levels.