Villonodular synovitis is an extremely rare condition of the synovial
membrane in the dog, A 10-year-old, neutered crossbreed was presented
with bilateral, progressive hindlimb lameness, Periarticular swelling
was noted in both stifle joints. No craniocaudal instability was noted
. Radiographs showed massive intra-articular soft tissue proliferation
in both joints, with no bony involvement. Arthrocentesis was unsucces
sful, Exploratory arthrotomy of the left stifle revealed a greatly thi
ckened, florid, proliferative synovial membrane, An incisional biopsy
was carried out and the histopathological diagnosis was chronic active
villonodular synovitis, A radical synovectomy was carried out in the
right stifle joint 10 days later. Corticosteroid treatment was initiat
ed 10 days after the second surgery and continued for six weeks, with
a continuous clinical improvement. Eighteen months after discontinuati
on of the steroid therapy, the owners reported no recurrence of clinic
al signs although a mild stiffness was still present.