People residing in schistosome endemic areas are often infected with other
parasites. The interaction of the parasites in the host has important impli
cations in the development of acquired immunity to schistosomiasis, and sch
istosome immuno-epidemiology. An analysis of specific anti-schistosome egg
responses in children coinfected with schistosomiasis and malaria shows tha
t malaria positive children produce significantly more anti-schistosome IgE
and IgG3 than schistosome infected children who are negative for malaria.