Effect of Ocimum sanctum roots extract on swimming performance in mice

Citation
Tk. Maity et al., Effect of Ocimum sanctum roots extract on swimming performance in mice, PHYTOTHER R, 14(2), 2000, pp. 120-121
Citations number
8
Categorie Soggetti
Pharmacology & Toxicology
Journal title
PHYTOTHERAPY RESEARCH
ISSN journal
0951418X → ACNP
Volume
14
Issue
2
Year of publication
2000
Pages
120 - 121
Database
ISI
SICI code
0951-418X(200003)14:2<120:EOOSRE>2.0.ZU;2-3
Abstract
The effect of a methanol extract, obtained from the roots of Ocimum sanctum , on mouse swimming performance were studied using three different doses. O n the basis of our findings, a high dose (400 mg/kg, i.p.) of the extracts of Ocimum sanctum increased the swimming time suggesting a central nervous system stimulant and/or antistress activity. The effect produced by the ext ract was comparable to that of desipramine, an antidepressant drug. Copyrig ht (C) 2000 John Wiley & Sons, Ltd.