This article reports the findings of a study that attempted to elucidate wh
ether pulsed magnetic energy stimulates neovascularization in vivo, using a
microsurgically created arterial loop model in a prospective randomized tr
ial of 108 rats (n = 12/group). Pulsed magnetic energies of 0.1 and 2.0 gau
ss were applied immediately postoperatively and for 4, 8, and 12 weeks, res
pectively, with a statistically significant increase in neovascularization
among the treated animals compared with control rats. The study provides a
starting point for future study and evaluation of the stimulation of angiog
enesis with the use of pulsed magnetic energy and suggests a possible use o
f this modality to increase the quality of revascularized tissue.