Juvenile spondylarthropathy

Citation
C. Job-deslandre, Juvenile spondylarthropathy, PRESSE MED, 29(9), 2000, pp. 510-516
Citations number
37
Categorie Soggetti
General & Internal Medicine","Medical Research General Topics
Journal title
PRESSE MEDICALE
ISSN journal
07554982 → ACNP
Volume
29
Issue
9
Year of publication
2000
Pages
510 - 516
Database
ISI
SICI code
0755-4982(20000311)29:9<510:JS>2.0.ZU;2-C
Abstract
Epidemiology: Juvenile spondylarthropathy accounts for about 20% of all cas es of chronic juvenile idiopathic arthritis. The spondyloarthropathy concep t includes chronic inflammatory rheumatismal conditions involving the spine , peripheral joints, and tendon insertions. There is an HLA B27 linkage and the condition predominates in boys, mean age 11 years. Clinical presentation: The usual clinical signs are asymmetrical involvemen t of the joints of the lower limbs associated in 30 to 50% of the cases wit h enthesiopathy. The diagnosis is based on the B Amor criteria and ESSG. Th e clinical course follows an episodic pattern in 80% of the cases. Treatment: Nonsteroidal antiinflammatory drugs and local care are used. Sul fasalazine can be useful but its efficacy has not been proven. The function al prognosis is relatively good; spinal ankylosis is uncommon and hip invol vement (destructive coxitis) occur in 30% of patients. About 80% of the pat ients have minor or no diability after a 10-year course.