OBJECTIVE: To elaborate a therapeutic theme far desmoid tumors developing w
ithin the mesenteric Foot These uncommon and often unrecognized tumors are
difficult to treat as they lie very dose to the superior mesenteric vessels
.
PATIENTS AND METHODS: Retrospective analysis of 14 cases treated in our cen
ter over the last 20 years and a review of the literature
RESULTS: The analysis led to the development of a therapeutic theme Patient
s are placed under regular surveillance to detect any progression of the me
senteric root desmoid tumor. In case of progression, surgery should be prop
osed as often as possible in spite of the real difficulty of this surgery.
When the tumor is unresectable, hormone therapy, sulindac, chemotherapy and
radiotherapy can be proposed as appropriate.
CONCLUSION: Based on the available literature, the proposed decisional tree
is a helpful management teal. This theme should be validated with the help
of a National Observatory focusing on this rare disease.