BACKGROUND: Malignant melanoma are uncommon in children and are sometimes d
ifficult to distinguish from Spitz nevi. Histological diagnosis is particul
arly difficult
CASE REPORT: Three prepuberty children (aged 14, 10 and 14 years) underwent
excision of suspicious nevi found at pathology examina tion to be malignan
t melanomas. After complementary treatment the recurrence-free survival has
been 18, 14 and 4 years respectively
DISCUSSION: Clinical signs of malignant melanomas are unspecific. As in adu
lts, any modification in a melanic lesion should led to excision and pathol
ogy examination. In the literature, there is often a confusion between mali
gnant melanoma developing in children and young adults making it difficult
to determine the prognosis of the childhood disease. Prognosis of cutaneous
malignant melanomas is generally good (excluding giant nevi and congenital
malignant melanoma).