Topological estimation of proton-ligand formation constants of potential antitumour agents: Salicylhydroxamic acids

Authors
Karmarkar, S Khadikar, PV Agrawal, VK Mathur, KC Mandloi, M Joshi, S
Citation
S. Karmarkar et al., Topological estimation of proton-ligand formation constants of potential antitumour agents: Salicylhydroxamic acids, P I A S-CH, 112(1), 2000, pp. 43-49
Citations number
15
Categorie Soggetti
Chemistry
Journal title
PROCEEDINGS OF THE INDIAN ACADEMY OF SCIENCES-CHEMICAL SCIENCES
ISSN journal
02534134 → ACNP
Volume
112
Issue
1
Year of publication
2000
Pages
43 - 49
Database
ISI
SICI code
0253-4134(200002)112:1<43:TEOPFC>2.0.ZU;2-H
Abstract
Proton-ligand formation constants of salicylhydroxamic acids (SHA) and thei r nuclear substituted derivatives have been estimated topologically using t he normalized Wiener index, referred to as mean square Wiener index (Wms). Regression analysis of the data indicates that Wms can be used successfully for estimating and monitoring proton-ligand formation constants.