Citation
Sh. Lee et al., An efficient and convenient synthesis of 5-formylsalicylaldehyde, SYN COMMUN, 30(6), 2000, pp. 1003-1008
Citations number
14
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNTHETIC COMMUNICATIONS
ISSN journal
00397911
→ ACNP
Volume
30
Issue
6
Year of publication
2000
Pages
1003 - 1008
Database
ISI
SICI code
0039-7911(2000)30:6<1003:AEACSO>2.0.ZU;2-Z
Abstract
5-Formylsalicylaldehyde 1, which is a key intermediate of spiropyran dye an
d a recently developed insulin sensitivity enhancer (ISE) compounds, was pr
epared from 5-iodosalicylaldehyde by the palladium-catalyzed coupling react
ion with ethyl acrylate followed by ozonolysis in high overall yield (92%).