The presence of cholestanyl substituents in hydraphile channels inhibits cation transport in the phospholipid bilayer

Authors
Meadows, ES Abel-Santos, E Frankel, DC Gokel, GW
Citation
Es. Meadows et al., The presence of cholestanyl substituents in hydraphile channels inhibits cation transport in the phospholipid bilayer, TETRAHEDR L, 41(12), 2000, pp. 1871-1875
Citations number
19
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
12
Year of publication
2000
Pages
1871 - 1875
Database
ISI
SICI code
0040-4039(20000318)41:12<1871:TPOCSI>2.0.ZU;2-R
Abstract
The presence of steroids within a synthetic, cation channel model compound restricts or prevents the passage of Na+ through the phospholipid bilayer o wing to collapse of the pore induced by hydraphobic contacts (C) 2000 Elsev ier Science Ltd. All rights reserved.