Barium-impregnated polyethylene spheres are an alternative contrast agent f
or radiographic studies of the gastrointestinal tract. The spheres are a pr
actical, efficient, and relatively inexpensive way to diagnose a number of
relatively common gastrointestinal conditions. They are most useful in the
diagnosis of chronic conditions. Radiographic interpretation relies on a th
orough understanding of the pathophysiology of gastrointestinal disease and
how various disease states influence gastrointestinal function.