Biomimetic polyesters and their role in ion transport across cell membranes

Authors
Jedlinski, Z Kurcok, P Adamus, G Juzwa, M
Citation
Z. Jedlinski et al., Biomimetic polyesters and their role in ion transport across cell membranes, ACT BIOCH P, 47(1), 2000, pp. 79-85
Citations number
20
Categorie Soggetti
Biochemistry & Biophysics
Journal title
ACTA BIOCHIMICA POLONICA
ISSN journal
0001527X → ACNP
Volume
47
Issue
1
Year of publication
2000
Pages
79 - 85
Database
ISI
SICI code
0001-527X(2000)47:1<79:BPATRI>2.0.ZU;2-O
Abstract
Syntheses of biomimetic low-molecular weight poly-(R)-3-hydroxybutanoate me diated by three types of supramolecular catalysts are presented. The utilit y of these synthetic polyesters for preparation of artificial channels in p hospholipid bilayers capable of sodium and calcium ion transport across cel l membranes, is discussed. Further studies on possible applications of thes e bio-polymers for manufacturing drugs of prolonged activity are under way.