Neurotransmitter-related genes and antipsychotic response: pharmacogenetics meets psychiatric treatment

Pharmacogenetic research into neurotransmitter-related genes is helping to unravel genetic factors that determine antipsychotic response, Several gene tic mutations in neurotransmitter receptors targeted by antipsychotic drugs have been found to be related to clinical response, Modern molecular genet ic techniques will facilitate the identification of those mutations that de termine treatment response. Future psychiatric prescription will include th e genetic characterization of neurotransmitter receptors for the selection of the most beneficial drug according to the individual's pharmacogenetic p rofile.