This review examines how molecular markers can be used to increase our unde
rstanding of the mechanisms of plant resistance to insects and develop inse
ct resistant crops. We provide a brief description of the types of molecula
r markers currently being employed, and describe how they can be applied to
identify and track genes of interest in a marker-assisted breeding program
. A summary of the work reported in this field of study, with examples in w
hich molecular markers have been applied to increase understanding of the m
echanistic and biochemical bases of resistance in potato and maize plant/pe
st systems, is provided. We also describe how molecular markers can be appl
ied to develop more durable insect-resistant crops. Finally, we identify ke
y areas in molecular genetics that we believe will provide exciting and pro
ductive research opportunities for those working to develop insect-resistan
t crops.